Which schedule contains Tylenol #2, Tylenol #3, Tylenol #4, Lortab, Vicodin?

• A. Schedule II
• B. Schedule III
• C. Schedule IV
• D. Schedule V

Answer: (B)

Controlled substances are organized by abuse potential and medical use. The opioid-containing combinations that pair acetaminophen with a moderate amount of codeine or hydrocodone have a recognized medical use but a lower abuse potential than stronger, pure opioid products, so they’re placed in a middle schedule. Tylenol with codeine formulations (Tylenol #2, #3, #4) and acetaminophen with hydrocodone (Lortab, Vicodin) fit this category because the added acetaminophen and limited opioid strength reduce their abuse risk compared with Schedule II opioids. Therefore, these drugs are classified as Schedule III.